SCHEMBL20547958

SCHEMBL20547958

CCCCCC(S)N1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
MAPT P10636 2/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.35
OPRM1 P35372 1/20 0.33
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563864 0.85 SLC6A3 (0.37) HRH3SLC6A2SLC6A4SLC6A3
SCHEMBL23509964 0.80 KCNH2 (0.39) HRH3MAPTMAPK1NPSR1MEN1
SCHEMBL28729351 0.79 KCNH2 (0.41) HRH3MAPTMAPK1NPSR1MEN1
SCHEMBL4288268 0.79 KCNH2 (0.41) HRH3MAPTMAPK1NPSR1MEN1
SCHEMBL9370536 0.78 HRH3 (0.40) HRH3L3MBTL1MAPTMAPK1NPSR1
SCHEMBL24688643 0.78 HRH3 (0.40) HRH3L3MBTL1MAPTMAPK1NPSR1
SCHEMBL3160023 0.78 HRH3 (0.40) HRH3L3MBTL1MAPTMAPK1NPSR1
SCHEMBL23032896 0.77 HRH3 (0.39) HRH3L3MBTL1MAPTMAPK1NPSR1
SCHEMBL22877461 0.77 HRH3 (0.42) HRH3L3MBTL1MAPTMAPK1NPSR1
SCHEMBL24604493 0.77 OPRM1 (0.39) HRH3L3MBTL1MAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209191-A1 PROCESS FOR REGENERATING A MONOLITHIC, MACRO-STRUCTURAL, INTER-PENETRATING ELASTOMER NETWORK MORPHOLOGY FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2024-06-27 US disclosed
US-20240110060-A1 INTER-PENETRATING ELASTOMER NETWORK DERIVED FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2024-04-04 US disclosed
US-20240101798-A1 INTER-PENETRATING ELASTOMER NETWORK DERIVED FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2024-03-28 US disclosed
CN-111479870-B Interpenetrating elastomer network derived from ground tire rubber particles 威廉·B·克 2024-03-19 CN disclosed
US-11840622-B2 Process for regenerating a monolithic, macro-structural, inter-penetrating elastomer network morphology from ground tire rubber particles COE WILLIAM B (US) 2023-12-12 US disclosed
US-11781018-B2 Inter-penetrating elastomer network derived from ground tire rubber particles COE WILLIAM B (US) 2023-10-10 US disclosed
US-11753530-B2 Inter-penetrating elastomer network derived from ground tire rubber particles COE WILLIAM B (US) 2023-09-12 US disclosed
CN-111032787-B Interpenetrating elastomer networks derived from ground tire rubber particles 威廉·B·克 2022-10-21 CN disclosed
CN-115124733-A Method for regenerating interpenetrating elastomer network morphology from ground tire rubber particles 威廉·B·克 2022-09-30 CN disclosed
US-20220186002-A1 PROCESS FOR REGENERATING A MONOLITHIC, MACRO-STRUCTURAL, INTER-PENETRATING ELASTOMER NETWORK MORPHOLOGY FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2022-06-16 US disclosed
US-10662320-B2 Process for regenerating a monolithic, macro-structural, inter-penetrating elastomer network morphology from ground tire rubber particles COE WILLIAM B (US) 2020-05-26 US disclosed
US-10626275-B2 Inter-penetrating elastomer network derived from ground tire rubber particles COE WILLIAM B (US) 2020-04-21 US disclosed
CN-111032787-A Interpenetrating elastomer networks derived from ground tire rubber particles 威廉·B·克 2020-04-17 CN disclosed
EP-3615605-A1 PROCESS FOR REGENERATING A MONOLITHIC, MACRO-STRUCTURAL, INTER-PENETRATING ELASTOMER NETWORK MORPHOLOGY FROM GROUND TIRE RUBBER PARTICLES Coe, William B. (US) 2020-03-04 EP disclosed
CN-110603289-A Process for regenerating monolithic, macrostructured, interpenetrating elastomer network morphology from ground tire rubber particles 威廉·B·克 2019-12-20 CN disclosed
WO-2019135815-A1 INTER-PENETRATING ELASTOMER NETWORK DERIVED FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2019-07-11 WO disclosed
US-20190055383-A1 INTER-PENETRATING ELASTOMER NETWORK DERIVED FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2019-02-21 US disclosed
US-20190040258-A1 INTER-PENETRATING ELASTOMER NETWORK DERIVED FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2019-02-07 US disclosed
WO-2019028286-A1 INTER-PENETRATING ELASTOMER NETWORK DERIVED FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2019-02-07 WO disclosed
WO-2018200340-A1 PROCESS FOR REGENERATING A MONOLITHIC, MACRO-STRUCTURAL, INTER-PENETRATING ELASTOMER NETWORK MORPHOLOGY FROM GROUND TIRE RUBBER PARTICLES COE WILLIAM B (US) 2018-11-01 WO disclosed