Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547958 | 0.85 | HRH3 (0.38) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL1101302 | 0.80 | SLC6A4 (0.32) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL24693242 | 0.77 | — | — | |
| SCHEMBL7330270 | 0.75 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL3302667 | 0.75 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL27615511 | 0.73 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL20445553 | 0.73 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL3308637 | 0.73 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL19272636 | 0.73 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL4886955 | 0.73 | GNAI3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |