Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208851 | 0.88 | GABRA1 (0.36) | ELANECTSG | |
| SCHEMBL9164495 | 0.84 | — | — | |
| SCHEMBL3232243 | 0.83 | GABRA1 (0.45) | KCNH2ELANE | |
| SCHEMBL7857695 | 0.83 | — | — | |
| SCHEMBL8932159 | 0.80 | TDP1 (0.30) | — | |
| SCHEMBL8301431 | 0.78 | — | — | |
| SCHEMBL7807775 | 0.78 | HDAC3 (0.39) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL5602948 | 0.73 | LIPG (0.42) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL5600911 | 0.72 | LIPG (0.45) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL8203510 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866569-A | A kind of N arylation synthetic methods of benzoxazolone and benzimidazolone | 常州大学 | 2017-06-20 | — | — | CN | claimed |
| CN-112789346-A | Negative hydrogen ion donors as additives to reduce low speed pre-ignition events | 雪佛龙奥伦耐有限责任公司 | 2021-05-11 | — | — | CN | disclosed |
| EP-3070092-B1 | 3-PHENYL-THIAZOLO[3,2-A]BENZIMIDAZOLE DERIVATIVES AS ALDEHYDE DEHYDROGENASE 1 (ALDH-1) MODULATORS FOR THE TREATMENT OF BREAST CANCER OR LEUKEMIA, AND FOR MANIPULATING CULTURED ALDH-1 POSITIVE BREAST CANCER OR LEUKEMIA CELLS | UNIV KING SAUD (SA) | 2018-11-07 | — | — | EP | disclosed |
| CN-106866569-A | A kind of N arylation synthetic methods of benzoxazolone and benzimidazolone | 常州大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-106866569-A | A kind of N arylation synthetic methods of benzoxazolone and benzimidazolone | 常州大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-1038586-C | Pyrazine derivatives and process for preparing same | OTSUKA PHARMA CO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| CN-1067053-A | Pyrazines derivatives and preparation method thereof | OTSUKA PHARMA CO LTD (JP) | 1992-12-16 | — | — | CN | disclosed |