SCHEMBL205506

SCHEMBL205506

O=C(NCc1ccc(C(F)(F)F)cc1)c1c(Cl)cccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.54
LSS P48449 1/20 0.53
ALDH2 P05091 6/20 0.53
MAPT P10636 1/20 0.52
MEN1 O00255 1/20 0.51
PLA2G1B P04054 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
GAA P10253 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51
LMNA P02545 1/20 0.51
HPGD P15428 1/20 0.51
TP53 P04637 1/20 0.50
MRGPRX4 Q96LA9 1/20 0.49
MLYCD O95822 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10389072 0.92 ALDH2 (0.58) MAPK14LSSALDH2MAPTGAA
SCHEMBL7854079 0.87 MAPT (0.50) MAPK14LSSALDH2MAPTMEN1
SCHEMBL10389082 0.86 MEN1 (0.70) MAPK14ALDH2MEN1PLA2G1BCYP1A2
SCHEMBL27340727 0.86 CNR1 (0.55) MAPTMEN1KMT2ALMNATP53
SCHEMBL5574721 0.85 P2RX7 (0.57) MAPK14LSSMAPTMEN1PLA2G1B
SCHEMBL6356701 0.84 MAPK14 (0.56) MAPK14LSSLMNAHPGDTP53
SCHEMBL27747072 0.84 MAPK14 (0.56) MAPK14LSSMLYCD
SCHEMBL10389407 0.83 SLC6A5 (0.50) MAPTMEN1CYP1A2CYP2C19KMT2A
SCHEMBL6362752 0.83 KMT2A (0.60) ALDH2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL6255530 0.83 ALDH2 (0.57) MAPK14ALDH2MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2436 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US claimed
US-12336537-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2025-06-24 US claimed
US-20250098677-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 US claimed
US-20250040552-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-02-06 US claimed
CN-118975562-A Fungicidal compositions 先正达农作物保护股份公司 2024-11-19 CN claimed
EP-4440315-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-10-09 EP claimed
US-20240284908-A1 Fungicidal Compositions SYNGENTA PARTICIPATIONS AG (CH) 2024-08-29 US claimed
CN-118354672-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-16 CN claimed
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 US claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP claimed
US-20110319435-A1 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-12-29 US claimed
WO-2011095492-A2 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-08-11 WO claimed
EP-2315522-A2 FORMATE-CONTAINING FUNGICIDE MIXTURES LANXESS Distribution GmbH (DE) 2011-05-04 EP claimed
EP-2153720-A1 Fungicide mixtures comprising formate LANXESS Distribution GmbH (DE) 2010-02-17 EP claimed
WO-2010015635-A2 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2010-02-11 WO claimed
EP-0314422-B1 N-PHENYLALKYLBENZAMIDE FUNGICIDES DOWELANCO (US) 1993-07-28 EP claimed
US-4957533-A THIOAMIDES, AMIDINES ELI LILLY AND COMPANY (US) 1990-09-18 US claimed
EP-0314422-A2 N-phenylalkylbenzamide fungicides DOWELANCO (US) 1989-05-03 EP claimed