Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
| ▸ | MTTP | P55157 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574721 | 0.89 | P2RX7 (0.57) | MAPK14HPGDLMNATP53LSS | |
| SCHEMBL27317568 | 0.86 | NPC1 (0.72) | HPGDLMNATP53NPC1RAB9A | |
| SCHEMBL8404892 | 0.84 | NPC1 (0.62) | MAPK14APEX1LSSNPC1RAB9A | |
| SCHEMBL205506 | 0.84 | MAPK14 (0.54) | MAPK14HPGDLMNATP53LSS | |
| SCHEMBL15686619 | 0.84 | KMT2A (0.70) | HPGDLMNAAPEX1GFERNPC1 | |
| SCHEMBL28146188 | 0.83 | LMNA (0.60) | MAPK14HPGDLMNANPC1RAB9A | |
| SCHEMBL6358889 | 0.83 | ALDH1A1 (0.65) | HPGDLMNAAPEX1GFERNPC1 | |
| SCHEMBL5860823 | 0.83 | NPC1 (0.71) | HPGDLMNATP53APEX1GFER | |
| SCHEMBL3577180 | 0.83 | KDM4E (0.68) | MAPK14HPGDAPEX1LSSALDH1A1 | |
| SCHEMBL29917968 | 0.81 | MAPK1 (0.51) | MAPK14HPGDLMNALSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | claimed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | claimed |
| CN-1033797-A | The N-phenylalkylbenzamidefungicides fungicides | LILLY CO ELI (US) | 1989-07-12 | — | — | CN | claimed |
| CN-101851244-B | Substituted phenyl keto enols as pesticides and herbicides | BAYER AG | 2013-08-21 | — | — | CN | disclosed |
| CN-103188935-A | Penflufen as a wood preservative against xylophagous basidiomycetes | LANXESS DEUTSCHLAND GMBH | 2013-07-03 | — | — | CN | disclosed |
| CN-102939967-A | Biocidal mixtures and use | LANXESS DEUTSCHLAND GMBH | 2013-02-27 | — | — | CN | disclosed |
| CN-102781977-A | SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS | DOW CORNING | 2012-11-14 | — | — | CN | disclosed |
| CN-102497776-A | Inorganic carrier materials containing nitrogen | LANXESS DEUTSCHLAND GMBH | 2012-06-13 | — | — | CN | disclosed |
| CN-102458106-A | Inorganic support material containing heterocyclic 3-membered ring compounds | LANXESS DEUTSCHLAND GMBH | 2012-05-16 | — | — | CN | disclosed |
| CN-1895048-B | Synergistic insecticidal mixtures | BAYER CROPSCIENCE AG | 2012-04-11 | — | — | CN | disclosed |
| CN-102293217-A | Insecticides based on selected neonicotinoids and strobilurins | — | 2011-12-28 | — | — | CN | disclosed |
| WO-1996000718-A1 | AMINO ACID DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-11 | — | — | WO | disclosed |
| WO-1995033717-A2 | HETEROCYCLIC IMINO DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-14 | — | — | WO | disclosed |
| CN-1110680-A | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BYLL GMBH (DE) | 1995-10-25 | — | — | CN | disclosed |
| CN-1105810-A | Azine derivatives | YASHIMA KAGAKU KOGYO KK (JP) | 1995-08-02 | — | — | CN | disclosed |
| CN-1103642-A | 3-aryl-4-hydroxy-delta3-dihydrofuransKetone derivatives | BAYER AG (DE) | 1995-06-14 | — | — | CN | disclosed |
| CN-1102757-A | Colloidally dispersible acive compound | BAYER AG (DE) | 1995-05-24 | — | — | CN | disclosed |
| WO-1995005367-A1 | 3-METHOXY-2-PHENYLACRYLIC ACID METHYL ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-23 | — | — | WO | disclosed |
| WO-1995000496-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-05 | — | — | WO | disclosed |
| CN-1033797-A | The N-phenylalkylbenzamidefungicides fungicides | LILLY CO ELI (US) | 1989-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | TFAM, CYP11B2, CYP11B1 | MAPK14 2671/4885HPGD 586/4885LMNA 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.