SCHEMBL20550846

SCHEMBL20550846

OCc1ncc(OCc2ccccc2)cn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 1/20 0.54
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
CYP2C19 P33261 1/20 0.53
PTGS2 P35354 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HIF1A Q16665 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
ALKBH1 Q13686 5/20 0.49
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
LTA4H P09960 1/20 0.49
EPHX2 P34913 1/20 0.49
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
MAOB P27338 3/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9130305 0.81 P4HTM (0.50) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL24323560 0.81 P4HTM (0.50) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL14067178 0.81 LMNA (0.62) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL12457985 0.81 APP (0.53) ALKBH1MAOBMAPTRAB9ASMN1; SMN2
SCHEMBL11034436 0.80 P4HTM (0.49) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL23121536 0.79 LMNA (0.53) P4HTMLMNARAB9ASMN1; SMN2L3MBTL1
SCHEMBL226721 0.79 P4HTM (0.59) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL18297527 0.77 MAOB (0.55) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL457443 0.77 P4HTM (0.53) P4HTMLMNACYP1A2PTGS1SLC6A2
SCHEMBL1713718 0.77 P4HTM (0.53) P4HTMLMNACYP1A2PTGS1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528804-A 2- { [2- (Phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, for example, for protecting plants 发现号收购集团 2025-02-28 CN disclosed
CN-119285538-A 2- { [2- (Phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, for example, for protecting plants 发现号收购集团 2025-01-10 CN disclosed
CN-114763357-B Indolopyrimidine tricyclic compound and preparation method and application thereof 中国科学院上海药物研究所 2024-06-18 CN disclosed
US-20240109860-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2024-04-04 US disclosed
US-11827616-B2 Heterocyclic compounds as pesticides DISCOVERY PURCHASER CORPORATION (US) 2023-11-28 US disclosed
US-11827616-B2 Heterocyclic compounds as pesticides DISCOVERY PURCHASER CORPORATION (US) 2023-11-28 US disclosed
US-11827616-B2 Heterocyclic compounds as pesticides DISCOVERY PURCHASER CORPORATION (US) 2023-11-28 US disclosed
CN-116601158-A Modulators of cystic fibrosis transmembrane conductance regulator 弗特克斯药品有限公司 2023-08-15 CN disclosed
CN-114763357-A Indolopyrimidine tricyclic compound and preparation method and application thereof 中国科学院上海药物研究所 2022-07-19 CN disclosed
WO-2022076622-A2 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-04-14 WO disclosed
EP-3619196-B1 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION BAYER CROPSCIENCE AG (DE) 2022-03-30 EP disclosed
EP-3619196-B1 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION BAYER CROPSCIENCE AG (DE) 2022-03-30 EP disclosed
EP-3619196-A1 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PEST-CONTROL AGENTS E.G. FOR THE PROTECTION OF PLANTS Bayer CropScience Aktiengesellschaft (DE) 2020-03-11 EP disclosed
CN-110869349-A 2- { [2- (phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, e.g. for protecting plants 拜耳作物科学股份公司 2020-03-06 CN disclosed
US-20200062729-A1 NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES DISCOVERY PURCHASER CORPORATION 2020-02-27 US disclosed
US-20200062729-A1 NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES DISCOVERY PURCHASER CORPORATION 2020-02-27 US disclosed
WO-2018202524-A1 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PEST-CONTROL AGENTS E.G. FOR THE PROTECTION OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827616-B2 Heterocyclic compounds as pesticides DDT, CHRM1, ACHE P4HTM 1378/4885LMNA 1324/4885CYP1A2 110/4885
US-20240109860-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, CHRM1, ACHE P4HTM 1378/4885LMNA 1324/4885CYP1A2 110/4885
US-20200062729-A1 NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES CHRM1, DDT, ACHE P4HTM 1551/4885LMNA 1636/4885CYP1A2 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.