Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 5/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550846 | 0.81 | P4HTM (0.54) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL6534698 | 0.80 | CYP1A2 (0.62) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL504815 | 0.80 | MAOB (0.60) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL1713718 | 0.80 | P4HTM (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL18297527 | 0.80 | MAOB (0.55) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL457443 | 0.80 | P4HTM (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL27965967 | 0.79 | NAAA (0.65) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL28646599 | 0.78 | RAB9A (0.52) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL875608 | 0.78 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL24323560 | 0.77 | P4HTM (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |