Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550846 | 0.81 | P4HTM (0.54) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL24323560 | 0.81 | P4HTM (0.50) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14067178 | 0.77 | LMNA (0.62) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL457443 | 0.77 | P4HTM (0.53) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL504815 | 0.77 | MAOB (0.60) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL1713718 | 0.77 | P4HTM (0.53) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL18297527 | 0.77 | MAOB (0.55) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8108514 | 0.76 | P4HTM (0.49) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL11034436 | 0.76 | P4HTM (0.49) | P4HTMLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28646599 | 0.76 | RAB9A (0.52) | P4HTMLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5444059-A | Anxiolytic agents | LABORATORIOS DEL. DR. ESTEVE, S.A. (ES) | 1995-08-22 | — | — | US | claimed |
| EP-0610140-A1 | 2- 4-(4-Azolylbutyl)-1-piperazinyl -5-hydroxypyrimidin derivatives, their preparation and their use als medicines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1994-08-10 | — | — | EP | claimed |
| US-5444059-A | Anxiolytic agents | LABORATORIOS DEL. DR. ESTEVE, S.A. (ES) | 1995-08-22 | — | — | US | disclosed |
| EP-0610140-A1 | 2- 4-(4-Azolylbutyl)-1-piperazinyl -5-hydroxypyrimidin derivatives, their preparation and their use als medicines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1994-08-10 | — | — | EP | disclosed |