Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185585 | 0.85 | HRH3 (0.70) | HRH3KEAP1NFE2L2LTA4HKCNH2 | |
| SCHEMBL3260775 | 0.80 | HRH3 (0.71) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL9935084 | 0.79 | CYP2D6 (0.66) | HRH3LTA4HKCNH2CYP1A2CYP2D6 | |
| SCHEMBL11649743 | 0.78 | HRH3 (0.56) | HRH3LTA4HTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9936830 | 0.77 | LTA4H (0.67) | HRH3KEAP1NFE2L2LTA4HKCNH2 | |
| SCHEMBL3130568 | 0.77 | HRH3 (0.49) | HRH3LTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21750630 | 0.77 | CHRNB2 (0.40) | HRH3KEAP1NFE2L2LTA4H | |
| SCHEMBL20550551 | 0.77 | CHEK2 (0.36) | HRH3LTA4H | |
| SCHEMBL9326150 | 0.77 | LTA4H (0.54) | HRH3KEAP1NFE2L2LTA4HKCNH2 | |
| SCHEMBL3082316 | 0.77 | LTA4H (0.46) | HRH3KEAP1NFE2L2LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018202525-A1 | PHENOXYETHANAMINE DERIVATIVES FOR CONTROLLING PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-08 | — | — | WO | disclosed |