Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 15/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22395360 | 0.82 | GAA (0.43) | LMNAGAA | |
| SCHEMBL20554184 | 0.82 | SMN1; SMN2 (0.51) | NR1H4LMNAGAA | |
| SCHEMBL23196210 | 0.81 | ALDH1A1 (0.51) | LMNAGAA | |
| SCHEMBL20031347 | 0.81 | LMNA (0.39) | NR1H4LMNAGAACYP3A4CYP2C8 | |
| SCHEMBL17851275 | 0.81 | NPC1 (0.51) | NR1H4LMNAGAATPMT | |
| SCHEMBL22229983 | 0.78 | NR1H4 (0.40) | NR1H4TPMT | |
| SCHEMBL22672582 | 0.77 | LMNA (0.37) | NR1H4LMNAGAA | |
| SCHEMBL20554083 | 0.77 | ALDH1A1 (0.51) | NR1H4TPMT | |
| SCHEMBL21264224 | 0.77 | GAA (0.48) | LMNAGAA | |
| SCHEMBL20031235 | 0.77 | RAB9A (0.41) | NR1H4LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3401315-A1 | FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | Guangzhou Henovcom Bioscience Co. Ltd. (CN) | 2018-11-14 | — | — | EP | disclosed |