Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870866 | 1.00 | GPR84 (0.40) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL21870765 | 0.90 | HTR2A (0.42) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL20555822 | 0.90 | HTR2A (0.42) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL22603075 | 0.90 | HTR2A (0.42) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL21870780 | 0.87 | GPR84 (0.41) | GPR84FFAR1ITGB2ICAM1ITGAL | |
| SCHEMBL20555924 | 0.87 | GPR84 (0.41) | GPR84FFAR1ITGB2ICAM1ITGAL | |
| SCHEMBL20555879 | 0.81 | HTR2A (0.41) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL18135246 | 0.81 | HTR2A (0.41) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL31427167 | 0.81 | HTR2A (0.41) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27273820 | 0.81 | HTR2A (0.43) | GPR84FFAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-10-29 | — | — | US | disclosed |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20180327793-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | AANAT, AADAT, TPH1 | GPR84 3894/4885FFAR1 3292/4885HTR2A 91/4885 |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | GPR84 3894/4885FFAR1 3292/4885HTR2A 91/4885 |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | AANAT, TPH1, AADAT | GPR84 3415/4885FFAR1 2270/4885HTR2A 29/4885 |
| US-20180327793-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | GPR84 3894/4885FFAR1 3292/4885HTR2A 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.