Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483557 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRKIF11HTTTDP1 | |
| SCHEMBL28024340 | 0.94 | ALDH1A1 (0.45) | ALDH1A1TSHRKIF11HTTCES2 | |
| SCHEMBL10870213 | 0.94 | ALDH1A1 (0.45) | ALDH1A1TSHRKIF11HTTCES2 | |
| SCHEMBL20556841 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TSHRKIF11HTTL3MBTL1 | |
| SCHEMBL11327202 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TSHRKIF11HTTL3MBTL1 | |
| SCHEMBL3927998 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRKIF11HTTTDP1 | |
| SCHEMBL2517312 | 0.74 | KIF11 (0.48) | ALDH1A1TSHRKIF11HTTTDP1 | |
| SCHEMBL27572321 | 0.74 | OPRM1 (0.49) | ALDH1A1TSHRKIF11TDP1L3MBTL1 | |
| SCHEMBL28003885 | 0.74 | KIF11 (0.48) | ALDH1A1TSHRKIF11HTTTDP1 | |
| SCHEMBL6478875 | 0.74 | KIF11 (0.48) | ALDH1A1TSHRKIF11HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180327343-A1 | COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2018-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327343-A1 | COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS | ELOVL5, FASN, ACSL5 | ALDH1A1 249/4885TSHR 4005/4885KIF11 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.