SCHEMBL20560743

SCHEMBL20560743

Fc1cccc(CCl)c1Br

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
GPR84 Q9NQS5 2/20 0.38
TAAR1 Q96RJ0 5/20 0.37
IDO1 P14902 2/20 0.34
FFAR1 O14842 1/20 0.34
HTT P42858 1/20 0.33
GRM2 Q14416 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MPO P05164 1/20 0.32
SLC6A4 P31645 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28528505 0.79 GABRA1 (0.46) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL29760840 0.79 GABRA1 (0.41) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL286672 0.79 GABRA1 (0.41) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL31145066 0.77 GPR84 (0.42) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL20516864 0.77 TAAR1 (0.46) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL6870883 0.77 GABRA1 (0.39) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL16941868 0.77 GABRA1 (0.70) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL595715 0.77 GPR84 (0.42) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL15352075 0.77 GABRA1 (0.44) GABRA1GABRB2GPR84TAAR1IDO1
SCHEMBL31192635 0.76 GABRA1 (0.42) GABRA1GABRB2TAAR1IDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108698982-B Fluorine atom-containing compound and use thereof 日产化学工业株式会社 2021-07-16 CN disclosed
EP-3404017-B1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF NISSAN CHEMICAL IND LTD (JP) 2020-05-13 EP disclosed
US-10336686-B2 Fluorine atom-containing compound and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-07-02 US disclosed
US-20190031600-A1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-31 US disclosed
EP-3404017-A1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF Nissan Chemical Industries, Ltd. (JP) 2018-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336686-B2 Fluorine atom-containing compound and use thereof ARF1, ARF5, ARFGAP1 GABRA1 2276/4885GABRB2 2827/4885GPR84 2180/4885
US-20190031600-A1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF ARF1, ARF5, ARFGAP1 GABRA1 2276/4885GABRB2 2827/4885GPR84 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.