Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801971 | 0.83 | TAAR1 (0.39) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL28528505 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL29760840 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL286672 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL31145066 | 0.77 | GPR84 (0.42) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL20560743 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL20516864 | 0.77 | TAAR1 (0.46) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL15352075 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL16941868 | 0.77 | GABRA1 (0.70) | GABRA1GABRB2GPR84TAAR1IDO1 | |
| SCHEMBL27484409 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2GPR84TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |