Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517696 | 0.81 | ALDH1A1 (0.40) | HSD17B10ALDH1A1TSHRCYP2C19HTT | |
| SCHEMBL4460861 | 0.77 | FEN1 (0.47) | HSD17B10ALDH1A1TSHRCYP2C19LDHA | |
| SCHEMBL8696587 | 0.77 | HSD17B10 (0.60) | HSD17B10ALDH1A1TSHRCYP2C19ADORA1 | |
| SCHEMBL8691780 | 0.76 | ALDH1A1 (0.58) | HSD17B10ALDH1A1TSHRCYP2C19LDHA | |
| SCHEMBL8692262 | 0.75 | HSD17B10 (0.47) | HSD17B10ALDH1A1TSHRCYP2C19LDHA | |
| SCHEMBL8691517 | 0.74 | HSD17B10 (0.46) | HSD17B10ALDH1A1TSHRCYP2C19ADORA2A | |
| SCHEMBL8691911 | 0.74 | LMNA (0.42) | HSD17B10ALDH1A1TSHRCYP2C19LDHA | |
| SCHEMBL8691464 | 0.73 | HSD17B10 (0.41) | HSD17B10ALDH1A1TSHRCYP2C19LDHA | |
| SCHEMBL3519074 | 0.73 | PIK3CD (0.44) | ALDH1A1TSHRHTTCCNE1CDK2 | |
| SCHEMBL8695153 | 0.72 | HSD17B10 (0.47) | HSD17B10ALDH1A1ADORA2ACCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12502362-B2 | Inhibitors of nucleotidyltransferase superfamily enzymes as antibiotics | SAINT LOUIS UNIVERSITY (US) | 2025-12-23 | — | — | US | disclosed |
| US-20200147086-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | SAINT LOUIS UNIVERSITY (US) | 2020-05-14 | — | — | US | disclosed |
| WO-2018213378-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | SAINT LOUIS UNIVERSITY (US) | 2018-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12502362-B2 | Inhibitors of nucleotidyltransferase superfamily enzymes as antibiotics | DNTT, APRT, RNGTT | HSD17B10 1539/4885ALDH1A1 1388/4885TSHR 2836/4885 |
| US-20200147086-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | DNTT, APRT, RNGTT | HSD17B10 1539/4885ALDH1A1 1388/4885TSHR 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.