SCHEMBL20565322

SCHEMBL20565322

NC(=O)c1cc(S(=O)(=O)C(F)(F)F)cc(S(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
KIF11 P52732 1/20 0.44
CA2 P00918 2/20 0.39
EPAS1 Q99814 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
LMNA P02545 2/20 0.35
GAA P10253 1/20 0.35
HSD11B1 P28845 1/20 0.35
SYK P43405 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP3A4 P08684 1/20 0.34
PARP1 P09874 1/20 0.34
ESPL1 Q14674 1/20 0.33
CES2 O00748 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28522802 0.89 CES2 (0.46) ALDH1A1KIF11CA2EPAS1KMT2A
SCHEMBL31443004 0.89 CES2 (0.46) ALDH1A1KIF11CA2EPAS1KMT2A
SCHEMBL2786905 0.82 GAA (0.51) ALDH1A1KIF11LMNAGAACYP3A4
SCHEMBL18513400 0.82 LCK (0.52) ALDH1A1KIF11CA2EPAS1MEN1
SCHEMBL2788803 0.80 CA2 (0.59) ALDH1A1KIF11CA2EPAS1MEN1
SCHEMBL1334378 0.80 ALDH1A1 (0.54) ALDH1A1KIF11CA2EPAS1MEN1
SCHEMBL732949 0.78 LCK (0.57) ALDH1A1KIF11CA2EPAS1MEN1
SCHEMBL5431855 0.76 KIF11 (0.64) ALDH1A1KIF11CA2CA12CA1
SCHEMBL18503859 0.74 LCK (0.44) ALDH1A1KIF11EPAS1MEN1KMT2A
SCHEMBL17057451 0.74 ALDH1A1 (0.45) ALDH1A1KIF11EPAS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3635022-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME Etna-Tec, Ltd (US) 2020-04-15 EP disclosed
WO-2018213850-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA-TEC, LTD (US) 2018-11-22 WO disclosed