SCHEMBL19271209

SCHEMBL19271209

O=C(CBr)NCCCC[C@H](NC(=O)COCCOCCNC(=O)CCC(NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)CCCS(=O)(=O)NC(=O)CCCc1nnn[nH]1)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.45
▸ FOLH1 Q04609 2/20 0.35
▸ ALB P02768 4/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ CCKAR P32238 5/20 0.34
▸ CCKBR P32239 5/20 0.34
▸ GLO1 Q04760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16478843 1.00 GLP1R (0.45) GLP1RFOLH1ALBCA9CCKAR
SCHEMBL15849999 1.00 GLP1R (0.45) GLP1RFOLH1ALBCA9CCKAR
SCHEMBL20567326 0.94 GLP1R (0.45) GLP1RFOLH1ALBCCKARCCKBR
SCHEMBL20567323 0.94 GLP1R (0.45) GLP1RFOLH1ALBCCKARCCKBR
SCHEMBL16180948 0.93 GLP1R (0.47) GLP1RFOLH1ALBCA9CCKAR
SCHEMBL16478775 0.93 GLP1R (0.45) GLP1RFOLH1ALBCA9CCKAR
SCHEMBL24734313 0.90 GLP1R (0.51) GLP1RCCKARCCKBR
SCHEMBL16093453 0.90 GLP1R (0.44) GLP1RCCKARCCKBR
SCHEMBL16142393 0.90 GLP1R (0.42) GLP1RCCKARCCKBRGLO1
SCHEMBL16180970 0.90 GLP1R (0.46) GLP1RCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170305994-A1 Antagonistic DR3 Ligands NOVO NORDISK AS (DK) 2017-10-26 — — US disclosed
US-20170239362-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170305994-A1 Antagonistic DR3 Ligands ACKR3, FPR3, FCGR3B GLP1R 1320/4885FOLH1 2136/4885ALB 3843/4885
US-20170239362-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM GLP1R 101/4885FOLH1 469/4885ALB 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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