SCHEMBL205674

SCHEMBL205674

CCC(=O)O[Si](OC(=O)CC)(OC(=O)CC)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.43
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TSHR P16473 2/20 0.35
KMT2A Q03164 2/20 0.35
ESR1 P03372 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD11B1 P28845 1/20 0.35
GLA P06280 1/20 0.35
DRD2 P14416 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8718823 0.85 CES2 (0.43) CES2CES1MAPTSMN1; SMN2L3MBTL1
SCHEMBL6054098 0.84 ELANE (0.43) ELANECES2CES1MAPTSMN1; SMN2
SCHEMBL19858510 0.82 ELANE (0.42) ELANECES2CES1MAPTSMN1; SMN2
SCHEMBL15738533 0.81 CYP1A2 (0.38) CES2CES1MAPTSMN1; SMN2GAA
SCHEMBL15738156 0.79 TRPM8 (0.38) CES2CES1MAPTSMN1; SMN2LMNA
SCHEMBL19858515 0.78 ELANE (0.39) ELANECES2CES1MAPTSMN1; SMN2
SCHEMBL29936830 0.78 TSHR (0.40) SMN1; SMN2LMNAKDM4ETSHRKMT2A
SCHEMBL9845210 0.78 ELANE (0.39) ELANECES2CES1MAPTSMN1; SMN2
SCHEMBL9488309 0.78 ELANE (0.39) ELANECES2CES1MAPTSMN1; SMN2
SCHEMBL15734468 0.78 GAA (0.43) CES2CES1MAPTL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP claimed
EP-2875074-B1 ORGANOSILOXANE COMPOSITIONS DOW SILICONES CORP (US) 2019-09-18 EP claimed
EP-3307455-B1 AEROSOL CAN, SET AND METHOD FOR FORMING A POLYMERIC MOULD RELEASE LAYER IN A MOULD CERANOVIS GMBH (DE) 2019-03-13 EP claimed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US claimed
EP-2155804-B1 A METHOD FOR MAKING PHENYLALKYLSILOXANES DOW SILICONES CORP (US) 2018-08-01 EP claimed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US claimed
US-20170174840-A1 MOISTURE CURABLE SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-06-22 US claimed
EP-2797692-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-11-05 EP claimed
WO-2013165552-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC (US) 2013-11-07 WO claimed
WO-2013158236-A2 MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-24 WO claimed
WO-2013101755-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
EP-2493984-A2 PAINTABLE ELASTOMER Dow Corning Corporation (US) 2012-09-05 EP claimed
EP-2493985-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2012-09-05 EP claimed
US-20120214902-A1 Paintable Elastomer DOW CORNING EUROPE SA (BE) 2012-08-23 US claimed
US-20120214925-A1 Organosiloxane Compositions DOW CORNING CORPORATION (US) 2012-08-23 US claimed
WO-2011051173-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2011-05-05 WO claimed
WO-2011051236-A2 PAINTABLE ELASTOMER DOW CORNING CORPORATION (US) 2011-05-05 WO claimed