SCHEMBL9488309

SCHEMBL9488309

CCC(=O)O[Si](OC(C)=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.37
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
TSHR P16473 2/20 0.35
KDM4E B2RXH2 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PIN1 Q13526 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
GBA1 P04062 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 2/20 0.33
ESR1 P03372 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054098 0.93 ELANE (0.43) ELANEALDH1A1MAPTCES2CES1
SCHEMBL132756 0.87 CES2 (0.43) ELANEALDH1A1MAPTCES2CES1
SCHEMBL704615 0.85 CES2 (0.41) ELANEALDH1A1MAPTCES2CES1
SCHEMBL11224422 0.83 MAPT (0.40) ALDH1A1MAPTCES2CES1TSHR
SCHEMBL205674 0.78 ELANE (0.43) ELANEALDH1A1MAPTCES2CES1
SCHEMBL8762487 0.77 CES2 (0.35) ELANEALDH1A1MAPTCES2CES1
SCHEMBL19858510 0.77 ELANE (0.42) ELANEMAPTCES2CES1TSHR
SCHEMBL9845210 0.76 ELANE (0.39) ELANEALDH1A1MAPTCES2CES1
SCHEMBL705143 0.74 ALDH1A1 (0.42) ELANEALDH1A1MAPTCES2CES1
SCHEMBL1746452 0.73 CES2 (0.49) CES2CES1TSHRKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-B Sealing material composition for LED 日产化学株式会社 2021-11-09 CN disclosed
US-5229037-A Molding materials, resilience SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-07-20 US disclosed