Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA12 | O43570 | 9/20 | 0.53 |
| ▸ | CA9 | Q16790 | 9/20 | 0.53 |
| ▸ | CA1 | P00915 | 8/20 | 0.53 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572730 | 0.85 | ALDH1A1 (0.61) | ALDH1A1HTTPLGCA2CA12 | |
| SCHEMBL6284986 | 0.82 | KMT2A (0.64) | ALDH1A1HTTCA2CA1KMT2A | |
| SCHEMBL27825837 | 0.82 | PTGS2 (0.50) | KMT2APOLBMAPTPKMMEN1 | |
| SCHEMBL7038709 | 0.82 | POLB (0.46) | ALDH1A1HTTPLGCA2CA12 | |
| SCHEMBL3536505 | 0.82 | POLB (0.71) | ALDH1A1HTTPLGCA2CA12 | |
| SCHEMBL28112129 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTTPLGCA2CA12 | |
| SCHEMBL1874816 | 0.79 | CA2 (0.59) | ALDH1A1HTTCA2CA12CA9 | |
| SCHEMBL964748 | 0.79 | CA2 (0.54) | ALDH1A1HTTPLGCA2CA12 | |
| SCHEMBL27790073 | 0.78 | CA2 (0.53) | CA2CA12CA9CA1CA14 | |
| SCHEMBL29224978 | 0.77 | MEN1 (0.66) | CA2CA12CA9CA1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180339963-A1 | ANTICONVULSANT CARBAMATE DERIVATIVES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2018-11-29 | — | — | US | claimed |
| CN-113943234-A | Preparation method of sulfonylphenylurea herbicide safener | 常州大学 | 2022-01-18 | — | — | CN | disclosed |
| US-20180339963-A1 | ANTICONVULSANT CARBAMATE DERIVATIVES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2018-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180339963-A1 | ANTICONVULSANT CARBAMATE DERIVATIVES | CNR2, GRIK5, GRIK4 | ALDH1A1 1380/4885HTT 1120/4885PLG 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.