Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871442 | 0.82 | MAPT (0.52) | POLBMAPTPKMKMT2AELANE | |
| SCHEMBL3291980 | 0.82 | PKM (0.47) | POLBMAPTPKMKMT2AELANE | |
| SCHEMBL20567459 | 0.82 | ALDH1A1 (0.59) | POLBMAPTPKMADAMTS4KMT2A | |
| SCHEMBL1279396 | 0.80 | MAPT (0.71) | POLBMAPTPKMKMT2AMEN1 | |
| SCHEMBL27825837 | 0.80 | PTGS2 (0.50) | POLBMAPTPKMADAMTS4KMT2A | |
| SCHEMBL6284986 | 0.80 | KMT2A (0.64) | POLBMAPTPKMADAMTS4KMT2A | |
| SCHEMBL28236914 | 0.78 | KMT2A (0.63) | KMT2AMEN1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL1373940 | 0.77 | THRB (0.49) | POLBMAPTPKMKMT2AELANE | |
| SCHEMBL28722526 | 0.77 | KDM4E (0.40) | ADAMTS4KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL5367144 | 0.76 | ALDH1A1 (0.51) | POLBMAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113577237-B | Application of peptoid compound in resisting multi-drug resistant bacteria, pan-drug resistant bacteria or total-drug resistant bacteria | 浙江大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-113024634-B | Peptoid compounds and application thereof in preparation of antibiotics | 浙江大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-114450294-A | Polypeptide with MMP2 inhibitory effect | 大正制药株式会社 | 2022-05-06 | — | — | CN | disclosed |
| CN-108349961-B | Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents | 西奈山伊坎医学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-113577237-A | Application of peptoid compound in resisting multi-drug-resistant bacteria, pan-drug-resistant bacteria or full-drug-resistant bacteria | 浙江大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113024634-A | Peptoid compounds and application thereof in preparation of antibiotics | 浙江大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-109302846-B | Indolinone compounds and their use in the treatment of fibrotic diseases | 莱斯彼维特有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-109302846-A | Indolinone compounds and their use in the treatment of fibrotic diseases | 莱斯彼维特有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-108349961-A | Heterocycle is limited tricyclic sulfonamide as antitumor and anticancer agent | 西奈山伊坎医学院 | 2018-07-31 | — | — | CN | disclosed |
| US-20030059826-A1 | SOLUBLE COMBINATORIAL LIBRARIES | SCRIPPS RESEARCH INSTITUTE, THE | 2003-03-27 | — | — | US | disclosed |
| EP-0772623-A1 | SOLUBLE COMBINATORIAL LIBRARIES | The Scripps Research Institute (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003418-A1 | SOLUBLE COMBINATORIAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-02-08 | — | — | WO | disclosed |