Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915550 | 0.83 | TLR7 (0.34) | PNPGDA | |
| SCHEMBL7765652 | 0.81 | TNNI3K (0.34) | — | |
| 2,6-Diaminopurine SCHEMBL7659157 | 0.75 | GDA (0.41) | PNPGDA | |
| SCHEMBL6545701 | 0.73 | GDA (0.34) | PNPGDA | |
| SCHEMBL8850 | 0.73 | GDA (0.33) | PNPGDA | |
| SCHEMBL11977311 | 0.73 | GDA (0.33) | PNPGDA | |
| 2,6-Diaminopurine SCHEMBL24052 | 0.72 | GDA (0.48) | PNPGDA | |
| 2,6-Diaminopurine SCHEMBL29444619 | 0.72 | GDA (0.48) | PNPGDA | |
| SCHEMBL10445918 | 0.72 | POLB (0.39) | — | |
| SCHEMBL2730453 | 0.71 | ALOX15 (0.33) | GDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200101048-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2020-04-02 | — | — | US | claimed |
| WO-2018217884-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-29 | — | — | WO | claimed |
| US-11452714-B2 | Antibacterial agents including histidine kinase inhibitors | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-09-27 | — | — | US | disclosed |
| US-11452714-B2 | Antibacterial agents including histidine kinase inhibitors | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-09-27 | — | — | US | disclosed |
| US-20200101048-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2020-04-02 | — | — | US | disclosed |
| US-20200101048-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2020-04-02 | — | — | US | disclosed |
| WO-2018217884-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-29 | — | — | WO | disclosed |
| WO-2018217884-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200101048-A1 | ANTIBACTERIAL AGENTS INCLUDING HISTIDINE KINASE INHIBITORS | PDXK, BLK, DCK | PNP 101/4885GDA 1184/4885 |
| US-11452714-B2 | Antibacterial agents including histidine kinase inhibitors | PDXK, BLK, DCK | PNP 101/4885GDA 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.