Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219009 | 0.76 | MAPT (0.40) | TDP1ALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL9319797 | 0.73 | TDP1 (0.54) | TDP1ALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL28475727 | 0.73 | MAPT (0.38) | TDP1ALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL31474641 | 0.73 | TDP1 (0.52) | TDP1ALDH1A1NPSR1CA9SMN1; SMN2 | |
| SCHEMBL6741088 | 0.71 | SMN1; SMN2 (0.47) | TDP1ALDH1A1MAPTSMN1; SMN2PDE7A | |
| SCHEMBL3599344 | 0.71 | SMN1; SMN2 (0.47) | TDP1ALDH1A1MAPTSMN1; SMN2PDE7A | |
| SCHEMBL1374438 | 0.70 | GPR35 (0.48) | TDP1ALDH1A1MAPTSMN1; SMN2PDE7A | |
| SCHEMBL1668133 | 0.70 | TDP1 (0.48) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11032366 | 0.70 | TSHR (0.52) | TDP1ALDH1A1MAPTSMN1; SMN2PDE7A | |
| SCHEMBL6737148 | 0.70 | SMN1; SMN2 (0.46) | TDP1ALDH1A1MAPTSMN1; SMN2PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY | 2011-03-03 | — | — | US | disclosed |
| WO-2009026184-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | TET1, ALKBH1, NQO1 | TDP1 776/4885ALDH1A1 127/4885MAPT 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.