Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414622 | 0.79 | RARB (0.41) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL15082353 | 0.79 | RARB (0.41) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL8776387 | 0.74 | RARB (0.44) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL16389608 | 0.72 | TRPA1 (0.37) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL5442565 | 0.71 | RARB (0.37) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL21574083 | 0.70 | MEN1 (0.46) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL15435465 | 0.70 | ALDH1A1 (0.38) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL3148661 | 0.69 | MEN1 (0.44) | TRPA1RARBRARGRARARXRA | |
| SCHEMBL15132004 | 0.68 | POLB (0.44) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL5441832 | 0.68 | TRPA1 (0.40) | TRPA1RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180339961-A1 | DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180339961-A1 | DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND USES THEREOF | RARB, RXRB, RXRA | TRPA1 4169/4885RARB 1/4885RARG 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.