Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | SERPINH1 | P50454 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086103 | 0.98 | ALDH1A1 (0.48) | ALDH1A1MAPTCA9KMT2AMEN1 | |
| SCHEMBL30810850 | 0.87 | ALDH1A1 (0.35) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL4087041 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTCA9KMT2AMEN1 | |
| SCHEMBL8838581 | 0.76 | ESR1 (0.42) | ALDH1A1MAPTCA9KMT2AMEN1 | |
| SCHEMBL10336137 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTCA9KMT2AMEN1 | |
| SCHEMBL8510918 | 0.75 | LMNA (0.46) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL146897 | 0.75 | LMNA (0.46) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| Silver SCHEMBL28878173 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAPTCA9KMT2AMEN1 | |
| SCHEMBL11696138 | 0.73 | LMNA (0.44) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| Fluoride SCHEMBL27406526 | 0.73 | LMNA (0.44) | ALDH1A1MAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6719902-B1 | TREATING AN ENVIRONMENTAL SITE WITH AN EFFECTIVE AMOUNT OF A COMPOSITION COMPRISING ONE OR MORE HYDROGENOTROPHIC BACTERIA AND ZERO-VALENT IRON | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-04-13 | — | — | US | claimed |
| WO-1998049106-A1 | FE(O)-BASED BIOREMEDIATION OF AQUIFERS CONTAMINATED WITH MIXED WASTES | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-11-05 | — | — | WO | claimed |
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY | 2011-03-03 | — | — | US | disclosed |
| WO-2009026184-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2009-02-26 | — | — | WO | disclosed |
| US-6719902-B1 | TREATING AN ENVIRONMENTAL SITE WITH AN EFFECTIVE AMOUNT OF A COMPOSITION COMPRISING ONE OR MORE HYDROGENOTROPHIC BACTERIA AND ZERO-VALENT IRON | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-04-13 | — | — | US | disclosed |
| WO-1998049106-A1 | FE(O)-BASED BIOREMEDIATION OF AQUIFERS CONTAMINATED WITH MIXED WASTES | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | TET1, ALKBH1, NQO1 | ALDH1A1 127/4885MAPT 3674/4885CA9 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.