Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019433 | 0.86 | MEN1 (0.58) | ABL1RIN1KMT2AMGLLMEN1 | |
| SCHEMBL21381625 | 0.86 | HSD11B1 (0.48) | ABL1RIN1KMT2AUSP30MEN1 | |
| SCHEMBL4192895 | 0.86 | RORC (0.48) | ABL1RIN1KMT2AUSP30MGLL | |
| SCHEMBL2882463 | 0.85 | KDM4E (0.51) | KMT2AUSP30GPR119MEN1KDM4E | |
| SCHEMBL9947987 | 0.84 | STS (0.54) | KMT2AMGLLGPR119MEN1KDM4E | |
| SCHEMBL17729534 | 0.83 | MAPT (0.50) | KMT2AUSP30MGLLGPR119MEN1 | |
| SCHEMBL19726024 | 0.83 | ABL1 (0.42) | ABL1RIN1KMT2AUSP30GPR119 | |
| SCHEMBL19726023 | 0.81 | ALDH1A1 (0.41) | ABL1RIN1KMT2AUSP30GPR119 | |
| SCHEMBL16225186 | 0.80 | ALDH1A1 (0.44) | ABL1RIN1KMT2AUSP30GPR119 | |
| SCHEMBL16662147 | 0.79 | LMNA (0.47) | ABL1RIN1KMT2AGPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |