SCHEMBL20569059

SCHEMBL20569059

C#Cc1ccc(OCCCO[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.39
CYP2D6 P10635 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP19A1 P11511 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
POLB P06746 2/20 0.32
DHFR P00374 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17088428 0.95 DUT (0.38) DUTCYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL19879751 0.92 DUT (0.37) DUTCYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL12573237 0.88 DUT (0.40) DUTKDM4EALDH1A1
SCHEMBL25369942 0.81 LTA4H (0.50) DUTCYP2D6CYP1A2CYP19A1CYP2C19
SCHEMBL20568979 0.81 APP (0.41) DUTCYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL578484 0.81 KDM4E (0.53) DUTKDM4EALDH1A1DHFRMAOB
SCHEMBL20204806 0.81 MAPT (0.47) DUTCYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL20487117 0.79 DUT (0.34) DUTHDAC8
SCHEMBL1629693 0.78 HRH3 (0.43) DUTCYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL4959621 0.78 DUT (0.39) DUTCYP2D6CYP1A2CYP19A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116135858-B Furanopyridone compound and application thereof 中国科学院广州生物医药与健康研究院 2025-04-01 CN disclosed
CN-116135858-A Furanopyridone compound and application thereof 中国科学院广州生物医药与健康研究院 2023-05-19 CN disclosed
WO-2018216822-A1 NOVEL IMIDAZOLE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD. (JP) 2018-11-29 WO disclosed