SCHEMBL19879751

SCHEMBL19879751

C#Cc1ccc(OCCO[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.37
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
EGFR P00533 1/20 0.32
ILK Q13418 1/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12573237 0.95 DUT (0.40) DUTALDH1A1KDM4EL3MBTL1APP
SCHEMBL20569059 0.92 DUT (0.39) DUTALDH1A1KDM4ECYP1A2CYP2D6
SCHEMBL17088428 0.91 DUT (0.38) DUTALDH1A1KDM4ECYP1A2CYP2D6
SCHEMBL5855905 0.86 MAOB (0.43) DUTALDH1A1KDM4ECA12CA1
SCHEMBL23754946 0.84 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTL3MBTL1SMN1; SMN2
SCHEMBL15831460 0.81 DRD2 (0.44) DUTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL5857320 0.81 MEN1 (0.45) ALDH1A1KDM4EMAPTCA12CA1
SCHEMBL20487117 0.81 DUT (0.34) DUTHDAC8
SCHEMBL24724730 0.81 KDM4E (0.39) DUTALDH1A1KDM4EMAPTEGFR
SCHEMBL275331 0.80 LTA4H (0.47) DUTCYP1A2CYP2D6CYP19A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116135858-B Furanopyridone compound and application thereof 中国科学院广州生物医药与健康研究院 2025-04-01 CN disclosed
CN-116135858-A Furanopyridone compound and application thereof 中国科学院广州生物医药与健康研究院 2023-05-19 CN disclosed
US-9896479-B2 Functionalized naphthalene fluorophores Kay M. Brummond (US) 2018-02-20 US disclosed