SCHEMBL20569271

SCHEMBL20569271

CSCc1ccc(C=O)o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
TSHR P16473 1/20 0.62
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 1/20 0.43
GAA P10253 1/20 0.42
CYP2E1 P05181 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2B6 P20813 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2A6 P11509 1/20 0.39
KDM4E B2RXH2 5/20 0.35
POLB P06746 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 4/20 0.33
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31121618 0.83 ALDH1A1 (0.61) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL18163839 0.78 CYP2E1 (0.48) CYP2E1CYP3A4CYP2D6CYP2C9CYP2B6
SCHEMBL157526 0.77
Aes-103 SCHEMBL31307749 0.77
Aes-103 SCHEMBL17513182 0.76 ALDH1A1 (0.88) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL6924355 0.75 ALDH1A1 (0.47) ALDH1A1TSHRL3MBTL1HTTGAA
Aes-103 SCHEMBL17872171 0.75 ALDH1A1 (0.96) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL8640022 0.75 ALDH1A1 (0.61) ALDH1A1TSHRL3MBTL1HTTGAA
Aes-103 SCHEMBL31307061 0.75 ALDH1A1 (0.96) ALDH1A1TSHRL3MBTL1HTTGAA
Aes-103 SCHEMBL1248422 0.75 ALDH1A1 (0.96) ALDH1A1TSHRL3MBTL1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136302-B2 Single step process for the synthesis of furan derivatives from carbohydrates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-10-05 US claimed
US-20210147374-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-05-20 US claimed
EP-3630739-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES Council of Scientific and Industrial Research (IN) 2020-04-08 EP claimed
WO-2018216030-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-11-29 WO claimed
US-20230242423-A1 EXTRACT OF PLANT POWDER, AND WATER PURIFIER DEXERIALS CORPORATION (JP) 2023-08-03 US disclosed
US-11136302-B2 Single step process for the synthesis of furan derivatives from carbohydrates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-10-05 US disclosed
US-11136302-B2 Single step process for the synthesis of furan derivatives from carbohydrates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-10-05 US disclosed
US-20210147374-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-05-20 US disclosed
US-20210147374-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-05-20 US disclosed
EP-3630739-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES Council of Scientific and Industrial Research (IN) 2020-04-08 EP disclosed
WO-2018216030-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147374-A1 A SINGLE STEP PROCESS FOR THE SYNTHESIS OF FURAN DERIVATIVES FROM CARBOHYDRATES DCXR, FBP1, HSD17B14 ALDH1A1 807/4885TSHR 4379/4885L3MBTL1 4885/4885
US-11136302-B2 Single step process for the synthesis of furan derivatives from carbohydrates FBP1, DCXR, G6PD ALDH1A1 875/4885TSHR 4562/4885L3MBTL1 4885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.