SCHEMBL20569296

SCHEMBL20569296

CN(c1ccc(N)cc1)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TDP1 Q9NUW8 4/20 0.45
CYP3A4 P08684 4/20 0.45
MAPK1 P28482 3/20 0.45
TP53 P04637 1/20 0.45
ALOX15 P16050 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.36
TSHR P16473 2/20 0.36
PSMD14 O00487 1/20 0.36
RECQL P46063 1/20 0.36
GFER P55789 1/20 0.36
EGFR P00533 1/20 0.35
PDGFRB P09619 1/20 0.35
KDR P35968 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16698000 0.81 PTGS2 (0.44) ALDH1A1TDP1MAPK1TP53TSHR
SCHEMBL796429 0.80 ALDH1A1 (0.64) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL4882444 0.77 ALDH1A1 (0.45) ALDH1A1TDP1CYP3A4MAPK1TP53
SCHEMBL795537 0.77 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL8973771 0.76 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL8119143 0.74 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4MAPK1TP53
SCHEMBL7877908 0.73 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4MAPK1TP53
SCHEMBL64766 0.73 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4MAPK1TP53
SCHEMBL21474106 0.73 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4MAPK1TP53
SCHEMBL14869755 0.73 NPC1 (0.47) ALDH1A1CYP3A4MAPK1L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260126453-A1 Mass Spectrometry Kit Including a Cross-linked Antibody or Fragment Thereof THE BINDING SITE GROUP LTD (GB) 2026-05-07 US disclosed
EP-4675278-A2 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE The Binding Site Group Limited (GB) 2026-01-07 EP disclosed
US-12461108-B2 Mass spectrometry kit including a cross-linked antibody or fragment thereof THE BINDING SITE GROUP LIMITED (GB) 2025-11-04 US disclosed
US-20230391851-A1 ANTIBODIES THE BINDING SITE GROUP LIMITED (GB) 2023-12-07 US disclosed
CN-116148479-A Mass spectrometry kit 拜恩顶赛集团有限公司 2023-05-23 CN disclosed
EP-3420362-B1 ANTIBODIES THE BINDING SITE GROUP LTD (GB) 2023-03-22 EP disclosed
US-20230080943-A1 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE THE BINDING SITE GROUP LIMITED (GB) 2023-03-16 US disclosed
EP-4123308-A1 MASS SPECTROMETRY KIT The Binding Site Group Limited (GB) 2023-01-25 EP disclosed
EP-3420361-B1 MASS SPECTROMETRY KIT THE BINDING SITE GROUP LTD (GB) 2023-01-04 EP disclosed
EP-4071478-A1 ASSAY FOR PLASMA CELL ASSSOCIATED DISEASE The Binding Site Group Limited (GB) 2022-10-12 EP disclosed
EP-3631452-B1 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE THE BINDING SITE GROUP LTD (GB) 2022-07-13 EP disclosed
EP-3631452-A1 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE The Binding Site Group Limited (GB) 2020-04-08 EP disclosed
CN-110945360-A Determination of plasma cell related diseases 结合点集团有限公司 2020-03-31 CN disclosed
US-20200096520-A1 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE BINDING SITE GROUP LIMITED, THE (GB) 2020-03-26 US disclosed
US-20190094239-A1 MASS SPECTROMETRY KIT MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2019-03-28 US disclosed
US-20190048064-A1 ANTIBODIES THE BINDING SITE GROUP LIMITED (GB) 2019-02-14 US disclosed
WO-2018215768-A1 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE THE BINDING SITE GROUP LIMITED (GB) 2018-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260126453-A1 Mass Spectrometry Kit Including a Cross-linked Antibody or Fragment Thereof IGLV6-57, IGSF11, FCGR3B ALDH1A1 2401/4885TDP1 3981/4885CYP3A4 3925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.