SCHEMBL796429

SCHEMBL796429

CN(c1ccccc1)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
MAPT P10636 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HTT P42858 1/20 0.44
EGFR P00533 1/20 0.43
PDGFRB P09619 1/20 0.43
KDR P35968 1/20 0.43
CDK2 P24941 1/20 0.42
GSK3B P49841 1/20 0.42
DYRK1A Q13627 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973771 0.96 ALDH1A1 (0.59) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL795537 0.87 ALDH1A1 (0.50) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL32688167 0.84 ALDH1A1 (0.47) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL8974883 0.84 TSHR (0.53) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL30568815 0.82 KMT2A (0.62) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL31398568 0.82 KMT2A (0.62) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL31398581 0.82 ALDH1A1 (0.45) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL31398570 0.81 GAA (0.51) ALDH1A1TDP1MAPTTSHRMAPK1
SCHEMBL31398572 0.81 MAPT (0.47) ALDH1A1TDP1MAPTCYP1A2CYP3A4
SCHEMBL31398577 0.81 ALDH1A1 (0.44) ALDH1A1TDP1MAPTCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025040698-A1 AZIDO-SUBSTITUTED HETEROAROMATIC ADDITIVES FOR PREPARING RECYCLABLE POLYMER COMPOSITIONS AND FOR UPCYCLING PLASTICS WASTES PARIS SCIENCES ET LETTRES (FR) 2025-02-27 WO disclosed
US-11851529-B2 Triazine ring-containing polymer, and thermoplastic article and optical part including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-12-26 US disclosed
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
WO-2022211025-A1 MOLDED BODY FOR COMMUNICATION EQUIPMENT, AND POLYCYANURATE 三菱ケミカル株式会社 2022-10-06 WO disclosed
US-11180612-B2 Triazine ring-containing polymer, and thermoplastic article and optical component including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-11-23 US disclosed
US-20200362112-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL PART INCLUDING SAME NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2020-11-19 US disclosed
US-20200362112-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL PART INCLUDING SAME NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2020-11-19 US disclosed
US-20200116896-A1 COMPOSITION, FILM, LENS, SOLID STATE IMAGING ELEMENT, AND COMPOUNDS FUJIFILM CORPORATION (JP) 2020-04-16 US disclosed
US-20200062907-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL COMPONENT INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-27 US disclosed
US-8895733-B2 Triazine-oxadiazoles NOVARTIS AG (CH) 2014-11-25 US disclosed
US-20140051676-A1 Triazine-oxadiazoles NOVARTIS AG (CH) 2014-02-20 US disclosed
EP-2616465-A1 TRIAZINE-OXADIAZOLES Novartis AG (CH) 2013-07-24 EP disclosed
WO-2012035023-A1 TRIAZINE-OXADIAZOLES NOVARTIS AG (CH) 2012-03-22 WO disclosed
EP-0629622-B1 S-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT ZENYAKU KOGYO KK (JP) 1998-11-11 EP disclosed
US-5489591-A INHIBITORS OF AROMATASE; TREATING ENDOMETRIOSIS, BREAST CANCER CYSTIC OVARIES ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 1996-02-06 US disclosed
EP-0629622-A1 s-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 1994-12-21 EP disclosed
US-4939243-A Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed
EP-0084849-B1 WATER SOLUBLE COPPER COMPLEXES OF DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-14 EP disclosed
EP-0084849-A2 Water soluble copper complexes of disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds UACA, F12, ERGIC1 ALDH1A1 1867/4885TDP1 3990/4885MAPT 1060/4885
US-20200116896-A1 COMPOSITION, FILM, LENS, SOLID STATE IMAGING ELEMENT, AND COMPOUNDS UACA, F12, ERGIC1 ALDH1A1 1867/4885TDP1 3990/4885MAPT 1060/4885
US-20140051676-A1 Triazine-oxadiazoles OPRK1, OPRD1, OPRL1 ALDH1A1 439/4885TDP1 4176/4885MAPT 2602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.