Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.48 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143286 | 0.84 | SIGMAR1 (0.44) | CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL7699859 | 0.78 | CYP11B1 (0.50) | CYP11B1CYP11B2HDAC3HDAC4HDAC1 | |
| SCHEMBL16719005 | 0.74 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL2780498 | 0.73 | HTT (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL20568983 | 0.73 | CYP11B1 (0.55) | CYP11B1CYP11B2 | |
| SCHEMBL20569330 | 0.69 | HMOX1 (0.40) | CYP11B1CYP11B2HMOX1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL6596671 | 0.69 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP2A6CYP19A1CYP2B6 | |
| SCHEMBL6599405 | 0.69 | CYP11B1 (0.58) | CYP11B1CYP11B2 | |
| SCHEMBL20570009 | 0.68 | CYP19A1 (0.71) | CYP11B1CYP11B2HMOX1CYP2A6CYP19A1 | |
| SCHEMBL3111412 | 0.67 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP2A6CYP19A1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |