Phosphoric Acid

Phosphoric Acid

SCHEMBL20573143

O=P(O)(O)O.Oc1c[nH]c2cc(Br)ccc12

nearest known ligand 0.51

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A known ✓ P35348 2/20 0.40
ADRA1B known ✓ P35368 2/20 0.40
CYP2A6 P11509 1/20 0.51
CHRNB2 P17787 1/20 0.45
CHRNA7 P36544 1/20 0.45
CHRNA4 P43681 1/20 0.45
IMPDH2 P12268 1/20 0.44
GUSB P08236 3/20 0.44
IDO1 P14902 1/20 0.41
METAP2 P50579 1/20 0.41
NR4A2 P43354 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
CCNB2 O95067 1/20 0.38
CDK1 P06493 1/20 0.38
CCNB1 P14635 1/20 0.38
PRKACA P17612 1/20 0.38
PRKACG P22612 1/20 0.38
PRKACB P22694 1/20 0.38
CSNK1A1 P48729 1/20 0.38
CSNK1D P48730 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2804219 0.91 CYP2A6 (0.55) CYP2A6CHRNB2CHRNA7CHRNA4IMPDH2
Phosphoric Acid SCHEMBL1232434 0.86 GPR84 (0.50) GUSBIDO1NR4A2GPR84PRKACA
Acetic Acid SCHEMBL25368692 0.85 CYP2A6 (0.50) CYP2A6CHRNB2CHRNA7CHRNA4IMPDH2
Phosphoric Acid SCHEMBL431773 0.79 GPR84 (0.54) GUSBIDO1NR4A2GPR84
Phosphoric Acid SCHEMBL1231445 0.79 GPR84 (0.54) IDO1GPR84
SCHEMBL1237991 0.76 GPR84 (0.58) GUSBIDO1NR4A2GPR84
SCHEMBL21291503 0.76 CYP2A6 (0.55) CYP2A6CHRNB2CHRNA7CHRNA4IMPDH2
SCHEMBL27828855 0.76 CYP2A6 (0.47) CYP2A6CHRNB2CHRNA7CHRNA4IMPDH2
Phosphoric Acid SCHEMBL233986 0.74 GPR84 (0.50) CYP2A6IMPDH2GPR84
Nonanoate SCHEMBL27828783 0.73 GPR84 (0.42) CHRNB2CHRNA7CHRNA4GPR84GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11505816-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same KIKKOMAN CORPORATION (JP) 2022-11-22 US disclosed
CN-108603215-B Culture medium for detecting staphylococcus aureus, staphylococcus aureus detection sheet having the same, and method for detecting staphylococcus aureus using the same 龟甲万株式会社 2022-10-14 CN disclosed
US-20210017566-A1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS, SHEET FOR DETECTING S. AUREUS COMPRISING SAME, AND METHOD FOR DETECTING S. AUREUS USING SAME KIKKOMAN CORPORATION (JP) 2021-01-21 US disclosed
US-10822632-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same DAI NIPPON PRINTING CO., LTD. (JP) 2020-11-03 US disclosed
EP-3409784-B1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS DAINIPPON PRINTING CO LTD (JP) 2020-10-07 EP disclosed
US-20190024136-A1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS, SHEET FOR DETECTING S. AUREUS COMPRISING SAME, AND METHOD FOR DETECTING S. AUREUS USING SAME KIKKOMAN CORPORATION (JP) 2019-01-24 US disclosed
EP-3409784-A1 MEDIUM FOR DETECTINGSTAPHYLOCOCCUS AUREUS Dai Nippon Printing Co., Ltd. (JP) 2018-12-05 EP disclosed