Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573262 | 0.91 | CTSA (0.42) | ERN1AKR1C3AKR1C2PTGS2SLC9A1 | |
| SCHEMBL20573165 | 0.84 | ERN1 (0.49) | ERN1PTGS2SLC9A1FFAR4ALDH1A1 | |
| SCHEMBL17797023 | 0.83 | ERN1 (0.40) | ERN1SLC9A1FFAR4LRRK2 | |
| SCHEMBL20573163 | 0.83 | CTSA (0.44) | ERN1SLC9A1PDE4APDE4BPDE4C | |
| SCHEMBL20573273 | 0.82 | ERN1 (0.41) | ERN1AKR1C3AKR1C2PTGS2SLC9A1 | |
| SCHEMBL20573268 | 0.82 | BCL9 (0.40) | ERN1SLC9A1FFAR4LRRK2SYK | |
| SCHEMBL20573264 | 0.80 | TUBB4A (0.50) | SLC9A1BACE1ALDH1A1MAPT | |
| SCHEMBL20573325 | 0.79 | APP (0.42) | ERN1AKR1C3AKR1C2SLC9A1 | |
| SCHEMBL17796980 | 0.79 | PTGDR2 (0.43) | FFAR4BACE1MAPT | |
| SCHEMBL17796967 | 0.78 | CHRM3 (0.38) | ERN1SLC9A1PIN1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |