Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573249 | 0.87 | CHRM3 (0.42) | CHRM3SLC9A1AKR1C3AKR1C2CTSA | |
| SCHEMBL17797023 | 0.86 | ERN1 (0.40) | ERN1CHRM3SLC9A1LRRK2CTSA | |
| SCHEMBL20573268 | 0.84 | BCL9 (0.40) | ERN1SLC9A1LRRK2FFAR4 | |
| SCHEMBL20573427 | 0.83 | L3MBTL1 (0.39) | ERN1CHRM3NPSR1L3MBTL1HPGD | |
| SCHEMBL20573157 | 0.82 | ERN1 (0.45) | ERN1SLC9A1PTGS2LRRK2AKR1C3 | |
| SCHEMBL20573325 | 0.82 | APP (0.42) | ERN1CHRM3SLC9A1AKR1C3AKR1C2 | |
| SCHEMBL17796980 | 0.81 | PTGDR2 (0.43) | FFAR4MAPT | |
| SCHEMBL20573165 | 0.81 | ERN1 (0.49) | ERN1SLC9A1PTGS2LRRK2FFAR4 | |
| SCHEMBL17796967 | 0.81 | CHRM3 (0.38) | ERN1CHRM3SLC9A1LRRK2CTSA | |
| SCHEMBL17797025 | 0.80 | PARP1 (0.42) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |