Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735405 | 0.97 | DAO (0.41) | MAOBLMNAGPR84ALDH1A1TSHR | |
| SCHEMBL12453115 | 0.95 | DAO (0.43) | MAOBLMNAALDH1A1DAO | |
| SCHEMBL963564 | 0.85 | KCNH2 (0.44) | MAOBLMNAALDH1A1TSHRDAO | |
| SCHEMBL8945004 | 0.85 | MAOB (0.43) | MAOBLMNAGPR84ALDH1A1MAOA | |
| SCHEMBL23387581 | 0.83 | GPR84 (0.37) | MAOBGPR84ALDH1A1MAOA | |
| SCHEMBL962354 | 0.83 | RORC (0.38) | MAOBLMNAGPR84MAOA | |
| SCHEMBL26038271 | 0.83 | CA2 (0.55) | ALDH1A1 | |
| SCHEMBL21192386 | 0.81 | LMNA (0.38) | MAOBLMNAALDH1A1TSHRNT5E | |
| SCHEMBL17797595 | 0.81 | LMNA (0.38) | LMNAALDH1A1TSHRNT5E | |
| SCHEMBL9239765 | 0.81 | NMT1 (0.45) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212641-B1 | THIAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2018-12-05 | — | — | EP | disclosed |