SCHEMBL20573243

SCHEMBL20573243

Cc1cc(C(C)C)c(-c2ccc(N)cc2)c(C2(c3cc(C)cc(C(C)C)c3-c3ccc(N)cc3)c3ccccc3-c3ccccc32)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
OPRK1 P41145 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PDK2 Q15119 9/20 0.36
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
ALK Q9UM73 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20573241 0.81 LMNA (0.49) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL24254783 0.69 SMN1; SMN2 (0.50) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL13326482 0.69 SMN1; SMN2 (0.50) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL19060980 0.69 SMN1; SMN2 (0.50) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL19217072 0.69 PDK2 (0.62) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL9342076 0.68 LMNA (0.41) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL20581822 0.67 KDM4E (0.56) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL21763823 0.67 PDK2 (0.56) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL7055099 0.67 LMNA (0.71) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL29579958 0.67 LMNA (0.71) LMNAMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629228-B2 Compositions of and methods for producing modified monomers and polyimides for sour mixed gas separation SAUDI ARABIAN OIL COMPANY 2023-04-18 US claimed
WO-2021202664-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 WO claimed
US-20210309803-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 US claimed
US-11642629-B2 Multi-layer composite gas separation membranes, methods for preparation, and use SAUDI ARABIAN OIL COMPANY 2023-05-09 US disclosed
US-11629228-B2 Compositions of and methods for producing modified monomers and polyimides for sour mixed gas separation SAUDI ARABIAN OIL COMPANY 2023-04-18 US disclosed
WO-2021202664-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 WO disclosed
US-20210309803-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 US disclosed
WO-2021188615-A1 MULTI-LAYER COMPOSITE GAS SEPARATION MEMBRANES, METHODS FOR PREPARATION, AND USE SAUDI ARABIAN OIL COMPANY (SA) 2021-09-23 WO disclosed
US-20210291120-A1 MULTI-LAYER COMPOSITE GAS SEPARATION MEMBRANES, METHODS FOR PREPARATION, AND USE SAUDI ARABIAN OIL COMPANY (SA) 2021-09-23 US disclosed
US-10913036-B2 Cardo-type co-polyimide membranes for sour gas feed separations from natural gas SAUDI ARABIAN OIL COMPANY (SA) 2021-02-09 US disclosed
US-20180345229-A1 Cardo-Type Co-Polyimide Membranes For Sour Gas Feed Separations From Natural Gas SAUDI ARABIAN OIL COMPANY (SA) 2018-12-06 US disclosed