SCHEMBL20573241

SCHEMBL20573241

Cc1cc(C2(c3cc(C)c(-c4ccc(N)cc4)c(C(C)C)c3)c3ccccc3-c3ccccc32)cc(C(C)C)c1-c1ccc(N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
OPRK1 P41145 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
PDK2 Q15119 5/20 0.36
ALK Q9UM73 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
PAX8 Q06710 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324920 0.81 ESR1 (0.49) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL20573243 0.81 LMNA (0.43) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL29580634 0.77 LMNA (0.50) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2050108 0.77 LMNA (0.50) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL3884293 0.75 SMN1; SMN2 (0.50) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2442386 0.74 LMNA (0.42) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL3874336 0.74 LMNA (0.42) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL29579662 0.72 ESR1 (0.59) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2044448 0.72 ESR1 (0.59) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL25251979 0.72 ESR1 (0.46) LMNAMAPTKDM4EMEN1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629228-B2 Compositions of and methods for producing modified monomers and polyimides for sour mixed gas separation SAUDI ARABIAN OIL COMPANY 2023-04-18 US claimed
WO-2021202664-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 WO claimed
US-20210309803-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 US claimed
US-11642629-B2 Multi-layer composite gas separation membranes, methods for preparation, and use SAUDI ARABIAN OIL COMPANY 2023-05-09 US disclosed
US-11629228-B2 Compositions of and methods for producing modified monomers and polyimides for sour mixed gas separation SAUDI ARABIAN OIL COMPANY 2023-04-18 US disclosed
WO-2021202664-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 WO disclosed
US-20210309803-A1 COMPOSITIONS OF AND METHODS FOR PRODUCING MODIFIED MONOMERS AND POLYIMIDES FOR SOUR MIXED GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 US disclosed
WO-2021188615-A1 MULTI-LAYER COMPOSITE GAS SEPARATION MEMBRANES, METHODS FOR PREPARATION, AND USE SAUDI ARABIAN OIL COMPANY (SA) 2021-09-23 WO disclosed
US-20210291120-A1 MULTI-LAYER COMPOSITE GAS SEPARATION MEMBRANES, METHODS FOR PREPARATION, AND USE SAUDI ARABIAN OIL COMPANY (SA) 2021-09-23 US disclosed
US-10913036-B2 Cardo-type co-polyimide membranes for sour gas feed separations from natural gas SAUDI ARABIAN OIL COMPANY (SA) 2021-02-09 US disclosed
US-20180345229-A1 Cardo-Type Co-Polyimide Membranes For Sour Gas Feed Separations From Natural Gas SAUDI ARABIAN OIL COMPANY (SA) 2018-12-06 US disclosed