Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573244 | 0.89 | PTGDR2 (0.45) | CHRM3NPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL17797025 | 0.88 | PARP1 (0.42) | SLC9A1SCN9ASCN10APARP1 | |
| SCHEMBL20573273 | 0.87 | ERN1 (0.41) | CHRM3AKR1C3AKR1C2CTSASLC9A1 | |
| SCHEMBL17797024 | 0.85 | CNR2 (0.44) | CHRM3NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL20573242 | 0.84 | TUBB4A (0.42) | CHRM3CTSAPTGDR2SLC9A1SCN9A | |
| SCHEMBL17796980 | 0.84 | PTGDR2 (0.43) | HTTPTGDR2MAPT | |
| SCHEMBL20573324 | 0.83 | PDE4D (0.45) | CHRM3PTGDR2SLC9A1SCN9A | |
| SCHEMBL20573250 | 0.83 | CHRM3 (0.43) | CHRM3HTTSMN1; SMN2CTSASLC9A1 | |
| SCHEMBL20573268 | 0.81 | BCL9 (0.40) | SYKSLC9A1SCN9A | |
| SCHEMBL20573165 | 0.80 | ERN1 (0.49) | NPC1RAB9ASMN1; SMN2HSD17B10SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |