Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644760 | 0.82 | HSP90AA1 (0.59) | ADORA2AADORA3ADORA2BKDM5BADORA1 | |
| SCHEMBL716343 | 0.82 | ADORA2A (0.42) | ALDH1A1ADORA2AADORA3ADORA2BKDM5B | |
| SCHEMBL11983534 | 0.79 | ADORA2A (0.42) | MEN1ALDH1A1KMT2AHPGDADORA2A | |
| SCHEMBL10051515 | 0.78 | MEN1 (0.60) | MEN1ALDH1A1KMT2AHPGDL3MBTL1 | |
| SCHEMBL13294776 | 0.76 | MAPT (0.40) | MEN1ALDH1A1KMT2AADORA2AADORA3 | |
| SCHEMBL28829244 | 0.75 | ADORA2A (0.34) | MEN1ALDH1A1KMT2AADORA2AADORA3 | |
| SCHEMBL28534710 | 0.74 | ALDH1A1 (0.53) | MEN1ALDH1A1KMT2AHPGDKDM5B | |
| SCHEMBL413907 | 0.72 | MEN1 (0.79) | MEN1ALDH1A1KMT2AHPGDL3MBTL1 | |
| SCHEMBL3564907 | 0.72 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2AHPGDL3MBTL1 | |
| SCHEMBL908398 | 0.71 | MEN1 (0.52) | MEN1ALDH1A1KMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555095-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| EP-3362451-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| CN-110446711-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2022-02-15 | — | — | CN | disclosed |
| US-11225477-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-01-18 | — | — | US | disclosed |
| US-10987354-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-02-23 | — | — | US | disclosed |
| CN-108276401-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-20200339564-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |
| US-20200299294-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-09-24 | — | — | US | disclosed |
| US-10717732-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-07-21 | — | — | US | disclosed |
| CN-108218873-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20200085822-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
| US-20180346463-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299294-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | POLRMT, EIF2AK2, POLM | MEN1 4473/4885ALDH1A1 3790/4885KMT2A 1637/4885 |
| US-20180346463-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | POLRMT, EIF2AK2, POLM | MEN1 4473/4885ALDH1A1 3790/4885KMT2A 1637/4885 |
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | EIF2AK2, POLRMT, ZC3HAV1 | MEN1 4172/4885ALDH1A1 4038/4885KMT2A 2123/4885 |
| US-10717732-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | POLRMT, EIF2AK2, POLM | MEN1 4473/4885ALDH1A1 3790/4885KMT2A 1637/4885 |
| US-20200339564-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | EIF2AK2, ZC3HAV1, MAVS | MEN1 4563/4885ALDH1A1 3638/4885KMT2A 1921/4885 |
| US-10987354-B2 | Inhibitors of influenza virus replication and uses thereof | ZC3HAV1, MAVS, POLRMT | MEN1 3901/4885ALDH1A1 3909/4885KMT2A 1239/4885 |
| US-11225477-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | POLRMT, EIF2AK2, POLM | MEN1 4473/4885ALDH1A1 3790/4885KMT2A 1637/4885 |
| US-20200085822-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | ZC3HAV1, MAVS, POLRMT | MEN1 3901/4885ALDH1A1 3909/4885KMT2A 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.