Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.53 |
| ▸ | USP2 | O75604 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445118 | 0.78 | MIF (0.56) | ALDH1A1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL29452986 | 0.76 | PIM1 (0.43) | ALDH1A1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL20576366 | 0.74 | MEN1 (0.42) | ALDH1A1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL14872151 | 0.73 | STING1 (0.40) | ALDH1A1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL1257940 | 0.72 | KMO (0.58) | MEN1KMT2ACLK4MAPTPIM1 | |
| SCHEMBL29392239 | 0.72 | ASIC3 (0.59) | ALDH1A1MEN1KMT2ACYP2C19TP53 | |
| SCHEMBL632053 | 0.72 | ASIC3 (0.59) | ALDH1A1MEN1KMT2ACYP2C19TP53 | |
| SCHEMBL716343 | 0.71 | ADORA2A (0.42) | ALDH1A1TP53CYP1A2HSD17B10ALOX15 | |
| SCHEMBL1644760 | 0.71 | HSP90AA1 (0.59) | KDM4EKDM5BCDK9 | |
| SCHEMBL3826204 | 0.71 | ABL1 (0.44) | CLK4MAPTKDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748915-B | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2021-03-26 | — | — | CN | disclosed |