Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431227 | 0.90 | L3MBTL1 (0.58) | L3MBTL1NPC1KMT2ATP53RAB9A | |
| SCHEMBL27750359 | 0.84 | L3MBTL1 (0.75) | L3MBTL1NPC1KMT2ATP53RAB9A | |
| SCHEMBL11128265 | 0.82 | L3MBTL1 (0.72) | L3MBTL1NPC1KMT2ATP53RAB9A | |
| SCHEMBL1806524 | 0.82 | L3MBTL1 (1.00) | L3MBTL1NPC1KMT2ATP53RAB9A | |
| SCHEMBL10609303 | 0.82 | KMT2A (0.51) | L3MBTL1NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL169689 | 0.82 | L3MBTL1 (0.72) | L3MBTL1NPC1KMT2ATP53RAB9A | |
| SCHEMBL8773638 | 0.81 | LMNA (0.51) | L3MBTL1NPC1KMT2ARAB9AMAPT | |
| SCHEMBL1310073 | 0.81 | LTA4H (0.50) | L3MBTL1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL881471 | 0.81 | L3MBTL1 (0.70) | L3MBTL1NPC1KMT2ATP53RAB9A | |
| SCHEMBL2717154 | 0.80 | MAPT (0.62) | L3MBTL1NPC1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634948-B1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INST NAT SANTE RECH MED (FR) | 2025-09-17 | — | — | EP | disclosed |
| EP-3634949-B1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INST NAT SANTE RECH MED (FR) | 2025-03-19 | — | — | EP | disclosed |
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-10-24 | — | — | US | disclosed |
| US-11607419-B2 | Inhibitors of RAC1 and uses thereof for inducing bronchodilatation | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2023-03-21 | — | — | US | disclosed |
| WO-2018224563-A9 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2021-04-22 | — | — | WO | disclosed |
| US-20210077508-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | NANTES UNIVERSITE (FR) | 2021-03-18 | — | — | US | disclosed |
| EP-3634948-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | Institut National de la Sante et de la Recherche Medicale (INSERM) (FR) | 2020-04-15 | — | — | EP | disclosed |
| EP-3634949-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | NANTES UNIVERSITE (FR) | 2020-03-26 | — | — | US | disclosed |
| WO-2018224560-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-13 | — | — | WO | disclosed |
| WO-2018224563-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-13 | — | — | WO | disclosed |
| EP-3412652-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-12 | — | — | EP | disclosed |
| EP-3412651-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-12 | — | — | EP | disclosed |
| CN-108368102-A | 2- amino -1,3,4- thiadiazines and antifungal agent based on 2- amino -1,3,4- oxadiazines | F2G有限公司 | 2018-08-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | RAC1, KRAS, CYRIB | L3MBTL1 1887/4885NPC1 1666/4885KMT2A 3254/4885 |
| US-11607419-B2 | Inhibitors of RAC1 and uses thereof for inducing bronchodilatation | RAC1, CYRIB, ARHGDIB | L3MBTL1 3400/4885NPC1 2075/4885KMT2A 4243/4885 |
| US-20210077508-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | RAC1, CYRIB, ARHGDIB | L3MBTL1 3400/4885NPC1 2075/4885KMT2A 4243/4885 |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | RAC1, KRAS, CYRIB | L3MBTL1 1887/4885NPC1 1666/4885KMT2A 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.