Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394296 | 0.88 | NPC1 (0.58) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL285622 | 0.88 | NPC1 (0.58) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Benzotriazole SCHEMBL6249062 | 0.82 | NPC1 (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Drometrizole SCHEMBL937718 | 0.76 | NPC1 (0.72) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL31267541 | 0.74 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL29494818 | 0.74 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL258759 | 0.74 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL2724167 | 0.74 | NPC1 (0.41) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL4979055 | 0.74 | NPC1 (0.43) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8849637 | 0.73 | KCNMA1 (0.47) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638705-B1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC (CH) | 2024-02-28 | — | — | EP | disclosed |
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| US-20200405474-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON RESEARCH, LTD. | 2020-12-31 | — | — | US | disclosed |
| US-10806566-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2020-10-20 | — | — | US | disclosed |
| US-20180353285-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC. (CH) | 2018-12-13 | — | — | US | disclosed |