Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394296 | 1.00 | NPC1 (0.58) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Benzotriazole SCHEMBL20580212 | 0.88 | NPC1 (0.46) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL258759 | 0.84 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL31267541 | 0.84 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL29494818 | 0.84 | NPC1 (0.66) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL2724167 | 0.84 | NPC1 (0.41) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL4979055 | 0.84 | NPC1 (0.43) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL13288139 | 0.83 | NPC1 (0.61) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL2146554 | 0.83 | NPC1 (0.64) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL10061927 | 0.83 | NPC1 (0.64) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | claimed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | claimed |
| EP-3805290-B1 | POLYMER MATERIAL AND INTRAOCULAR LENS | SHANGHAI FULO MEDICAL INSTR CO LTD (CN) | 2024-09-11 | — | — | EP | claimed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | claimed |
| CN-118240387-A | Mildew-proof sponge material and preparation method thereof | 扬州中天海绵有限公司 | 2024-06-25 | — | — | CN | claimed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | claimed |
| WO-2023228055-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | WO | claimed |
| US-20230374306-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-23 | — | — | US | claimed |
| CN-116462794-A | Polymer and preparation method and application thereof | 天津世纪康泰生物医学工程有限公司 | 2023-07-21 | — | — | CN | claimed |
| US-6210438-B1 | HAVING ANTERIOR SURFACE MATERIAL DIFFERENT FROM ARYL ACRYLIC HYDROPHOBIC COPOLYMER POSTERIOR SURFACE MATERIAL, FOR POSTERIOR CAPSULE OPACIFICATION RISK REDUCTION, A CROSS-LINKING AGENT, UV-ABSORBERS AND BLUE-LIGHT BLOCKING | ALCON LABORATORIES, INC. | 2001-04-03 | — | — | US | claimed |
| EP-1079870-A1 | BICOMPOSITE INTRAOCULAR LENS AND METHOD FOR ITS PREPARATION | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999052571-A1 | BICOMPOSITE INTRAOCULAR LENS AND METHOD FOR ITS PREPARATION | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| EP-0578739-B1 | BIFOCAL INTRAOCULAR LENS WITH SPHERICAL ABERRATION CORRECTION | ALCON SURGICAL INC (US) | 1998-12-23 | — | — | EP | claimed |
| US-5693095-A | CROSSLINKED ACRYLIC COPOLYMERS, SUITABLE FOR SOFT, FOLDABLE EYE LENSES | ALCON LABORATORIES, INC. (US) | 1997-12-02 | — | — | US | claimed |
| US-5674960-A | USEFUL FOR INTRAOCULAR LENSES THAT CAN BE INSERTED THROUGH A RELATIVELY SMALL INCISION | NESTLE S.A. (CH) | 1997-10-07 | — | — | US | claimed |
| EP-0485197-B1 | Polymers and their use for ophthalmic lenses | NESTLE SA (CH) | 1996-10-02 | — | — | EP | claimed |
| US-5403901-A | Intraocular lenses of a copolymer of 2-phenylethyl acrylate and 2-phenylethyl methacrylate crosslinked by butanediol diacrylate and modified by 1-(3'-methallyl-2'-hydroxy-5'-methylbenzotriazole; flexibility | NESTLE S.A. (CH) | 1995-04-04 | — | — | US | claimed |
| US-5217489-A | Bifocal intraocular lens | ALCON SURGICAL, INC. (US) | 1993-06-08 | — | — | US | claimed |
| EP-0485197-A1 | Polymers and their use for ophthalmic lenses | NESTLE S.A. (CH) | 1992-05-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | NPC1 3998/4885RAB9A 4835/4885POLB 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.