Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.41 |
| ▸ | RAB9A | P51151 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394296 | 0.84 | NPC1 (0.58) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL285622 | 0.84 | NPC1 (0.58) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29814388 | 0.80 | NPC1 (0.49) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL352438 | 0.80 | NPC1 (0.49) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL1098570 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2725437 | 0.75 | NPC1 (0.36) | NPC1RAB9APOLBLMNAKDM4E | |
| Benzotriazole SCHEMBL20580212 | 0.74 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL1101121 | 0.74 | ALDH1A1 (0.36) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL6941182 | 0.74 | RAB9A (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL22549010 | 0.73 | NPC1 (0.36) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206204-B2 | Process for preparing 2-hydroxyphenyl benzotriazole siloxane compounds | L'OREAL (FR) | 2015-12-08 | — | — | US | claimed |
| EP-2632905-B1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | ORÉAL L (FR) | 2015-05-27 | — | — | EP | claimed |
| EP-2632905-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'Oréal (FR) | 2013-09-04 | — | — | EP | claimed |
| US-20130204006-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2013-08-08 | — | — | US | claimed |
| WO-2012055064-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2012-05-03 | — | — | WO | claimed |
| US-9447123-B2 | Process for preparing 2-hydroxyphenyl alkenyl benzotriazole compounds; use of the said compounds obtained via the process in the synthesis of siloxane compounds containing a 2-hydroxyphenylbenzotriazole function | L'OREAL (FR) | 2016-09-20 | — | — | US | disclosed |
| US-9447123-B2 | Process for preparing 2-hydroxyphenyl alkenyl benzotriazole compounds; use of the said compounds obtained via the process in the synthesis of siloxane compounds containing a 2-hydroxyphenylbenzotriazole function | L'OREAL (FR) | 2016-09-20 | — | — | US | disclosed |
| US-9447123-B2 | Process for preparing 2-hydroxyphenyl alkenyl benzotriazole compounds; use of the said compounds obtained via the process in the synthesis of siloxane compounds containing a 2-hydroxyphenylbenzotriazole function | L'OREAL (FR) | 2016-09-20 | — | — | US | disclosed |
| EP-2632904-B1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION | ORÉAL L (FR) | 2016-03-23 | — | — | EP | disclosed |
| EP-2632904-B1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION | ORÉAL L (FR) | 2016-03-23 | — | — | EP | disclosed |
| US-9206204-B2 | Process for preparing 2-hydroxyphenyl benzotriazole siloxane compounds | L'OREAL (FR) | 2015-12-08 | — | — | US | disclosed |
| US-9206204-B2 | Process for preparing 2-hydroxyphenyl benzotriazole siloxane compounds | L'OREAL (FR) | 2015-12-08 | — | — | US | disclosed |
| EP-2632905-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'Oréal (FR) | 2013-09-04 | — | — | EP | disclosed |
| US-20130204006-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2013-08-08 | — | — | US | disclosed |
| US-20130204006-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2013-08-08 | — | — | US | disclosed |
| US-20130204006-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2013-08-08 | — | — | US | disclosed |
| WO-2012055064-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055064-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055063-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055063-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130204006-A1 | PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS | HRH3, PAH, HRH4 | NPC1 3800/4885RAB9A 4199/4885POLB 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.