SCHEMBL2058027

SCHEMBL2058027

C[Si](C)(C)COS(C)(=O)=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2057624 0.74 CA1 (0.32)
SCHEMBL3257422 0.74 CA2 (0.33) TSHR
SCHEMBL2058014 0.72 USP2 (0.55) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL28944644 0.69 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2057502 0.69 USP2 (0.64) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL496480 0.69 CA2 (0.35)
Ethane Dimethane Sulfonate SCHEMBL1336145 0.67 USP2 (0.75) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL783382 0.67 USP2 (0.56) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL8969411 0.67 TSHR (0.68) USP2TSHRKDM4EALDH1A1LMNA
Methanesulfonic Acid Ethyl Ester SCHEMBL5533648 0.65 CA1 (0.53) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114206951-B Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst containing the same, and polyolefin polymerized by using the catalyst 韩华思路信株式会社 2023-04-14 CN disclosed
CN-114746485-A Olefin polymer film and method for producing the same 韩华思路信株式会社 2022-07-12 CN disclosed
CN-114206951-A Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst containing the same, and polyolefin polymerized by using the catalyst 韩华思路信株式会社 2022-03-18 CN disclosed
CN-113242863-A Transition metal compound for olefin polymerization catalyst and olefin polymerization catalyst comprising the same 韩华思路信株式会社 2021-08-10 CN disclosed
CN-103875117-B Non-aqueous electrolyte and lithium secondary battery containing phosphono sulfoacid compound 三井化学株式会社 2016-08-17 CN disclosed
US-9353150-B2 Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-05-31 US disclosed
US-9065146-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2015-06-23 US disclosed
US-20140187500-A1 COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2014-07-03 US disclosed
US-8551662-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2013-10-08 US disclosed
US-8029935-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-10-04 US disclosed
US-20110229771-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-09-22 US disclosed
US-7981553-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-20110159380-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-06-30 US disclosed
US-20100227226-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-09 US disclosed
US-20100021823-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-01-28 US disclosed
US-7575833-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-18 US disclosed
US-20070238025-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-11 US disclosed
US-7223502-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-05-29 US disclosed
US-20050118512-A1 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187500-A1 COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES DNPEP, NPEPPS, PIN1 USP2 2505/4885TSHR 1676/4885KDM4E 2449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.