Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207559 | 0.81 | CHEK1 (0.41) | CTSSCTSKCHEK1 | |
| SCHEMBL208851 | 0.79 | HPGD (0.40) | CTSS | |
| SCHEMBL206266 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL17654340 | 0.69 | HPGD (0.46) | CTSSCTSK | |
| SCHEMBL205364 | 0.68 | MCHR1 (0.39) | — | |
| SCHEMBL3130600 | 0.68 | CHRNA7 (0.36) | CTSS | |
| SCHEMBL205730 | 0.68 | MCHR1 (0.40) | — | |
| SCHEMBL2697660 | 0.67 | HPGD (0.39) | CTSS | |
| SCHEMBL207006 | 0.67 | ALOX5 (0.45) | — | |
| SCHEMBL205538 | 0.67 | VCP (0.43) | CTSSCTSKCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088806-B2 | Thiazole compounds and methods of use | ACHILLION PHARMACEUTICALS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20070004711-A1 | Thiazole compounds and methods of use | ACHILLION PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004711-A1 | Thiazole compounds and methods of use | PIGS, CPT1A, SLC10A1 | CTSS 1721/4885CTSK 3395/4885CHEK1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.