Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667426 | 0.78 | KDM4A (0.38) | MTORPIK3CAPIK3CDPIK3CBPI4KA | |
| SCHEMBL30508771 | 0.77 | KCNJ1 (0.43) | NNMTSMN1; SMN2ALDH1A1GABRPGABRD | |
| SCHEMBL5302622 | 0.77 | KCNJ1 (0.43) | NNMTSMN1; SMN2ALDH1A1GABRPGABRD | |
| SCHEMBL18339567 | 0.76 | JUN (0.41) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL15142310 | 0.74 | NNMT (0.61) | KDM4ALRRK2NNMTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2177672 | 0.74 | GABRP (0.43) | KDM4ANNMTSMN1; SMN2ALDH1A1GABRP | |
| SCHEMBL3153355 | 0.74 | NNMT (0.55) | NNMTSMN1; SMN2ALDH1A1GABRPGABRD | |
| SCHEMBL26421526 | 0.73 | KDM4A (0.36) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL1458173 | 0.72 | MAPK1 (0.47) | NNMTALDH1A1HPGDMAPT | |
| SCHEMBL20588738 | 0.72 | SCN10A (0.41) | MTORPIK3CAPI4KAPI4KBNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638669-A1 | SUBSTITUTED PYRROLOPYRIDINE-DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018228920-A1 | SUBSTITUTED PYRROLOPYRIDINE-DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-12-20 | — | — | WO | disclosed |