Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 5/20 | 0.43 |
| ▸ | GABRD | O14764 | 5/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.43 |
| ▸ | GABRE | P78334 | 5/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL23496608 | 0.85 | KDM4E (0.48) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL698657 | 0.84 | KDM4E (0.52) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL3153355 | 0.81 | NNMT (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5302622 | 0.79 | KCNJ1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30508771 | 0.79 | KCNJ1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3174349 | 0.78 | NNMT (0.57) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL27507067 | 0.77 | GABRP (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20588738 | 0.74 | SCN10A (0.41) | KDM4EALDH1A1NNMT | |
| SCHEMBL20587647 | 0.74 | MTOR (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1458173 | 0.74 | MAPK1 (0.47) | KDM4ETSHRALDH1A1L3MBTL1NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118497761-A | Composition, and preparation method and application thereof | 华为技术有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-116570556-B | Compound sulfachlordazine sodium solution for treating escherichia coli and pasteurellosis infection of livestock and poultry and preparation method thereof | 郑州福源动物药业有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116570556-A | Compound sulfachlordazine sodium solution for treating escherichia coli and pasteurellosis infection of livestock and poultry and preparation method thereof | 郑州福源动物药业有限公司 | 2023-08-11 | — | — | CN | claimed |
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | ZHEJIANG UNIVERSITY (CN) | 2025-09-02 | — | — | US | disclosed |
| US-20250099462-A1 | Certain Triazolopyridines and Triazolopyrazines, Compositions Thereof and Methods of Use Therefor | HUTCHISON MEDIPHARMA LTD (CN) | 2025-03-27 | — | — | US | disclosed |
| CN-118497761-A | Composition, and preparation method and application thereof | 华为技术有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20240139182-A1 | Certain Triazolopyridines and Triazolopyrazines, Compositions Thereof and Methods of Use Therefor | HUTCHISON MEDIPHARMA LTD (CN) | 2024-05-02 | — | — | US | disclosed |
| US-11896592-B2 | Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor | HUTCHISON MEDIPHARMA LIMITED (CN) | 2024-02-13 | — | — | US | disclosed |
| EP-3697784-B9 | IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2023-12-27 | — | — | EP | disclosed |
| CN-116570556-B | Compound sulfachlordazine sodium solution for treating escherichia coli and pasteurellosis infection of livestock and poultry and preparation method thereof | 郑州福源动物药业有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-4265254-A2 | IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | Galapagos N.V. (BE) | 2023-10-25 | — | — | EP | disclosed |
| US-4151288-A | ANTHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |
| US-4137237-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4137234-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | PIK3R5, PIK3CA, PIK3R1 | GABRP 570/4885GABRD 1302/4885GABRA1 1336/4885 |
| US-11896592-B2 | Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor | TK2, TYMP, DPYD | GABRP 2580/4885GABRD 2728/4885GABRA1 2700/4885 |
| US-20250099462-A1 | Certain Triazolopyridines and Triazolopyrazines, Compositions Thereof and Methods of Use Therefor | KCNJ11, NISCH, CYP4Z1 | GABRP 938/4885GABRD 760/4885GABRA1 1149/4885 |
| US-20240139182-A1 | Certain Triazolopyridines and Triazolopyrazines, Compositions Thereof and Methods of Use Therefor | KCNJ11, NISCH, CYP4Z1 | GABRP 938/4885GABRD 760/4885GABRA1 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.