Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333919 | 0.98 | SLC9A1 (0.36) | SLC9A1SMPD1TBXAS1KDRGBA1 | |
| SCHEMBL3739734 | 0.69 | FABP4 (0.39) | TBXAS1PTGS1PTGS2 | |
| SCHEMBL960665 | 0.68 | TBXAS1 (0.40) | SMPD1TBXAS1KDRPTGS1PTGS2 | |
| SCHEMBL959796 | 0.68 | TBXAS1 (0.40) | SMPD1TBXAS1KDRPTGS1PTGS2 | |
| SCHEMBL20936481 | 0.67 | MEN1 (0.62) | SLC9A1SMPD1TBXAS1KDRPTGS1 | |
| SCHEMBL20915274 | 0.67 | MEN1 (0.62) | SLC9A1SMPD1TBXAS1KDRPTGS1 | |
| SCHEMBL293470 | 0.67 | TBXAS1 (0.34) | SLC9A1SMPD1TBXAS1KDRPTGS1 | |
| SCHEMBL20915328 | 0.67 | MEN1 (0.62) | SLC9A1SMPD1TBXAS1KDRPTGS1 | |
| SCHEMBL20936607 | 0.67 | MEN1 (0.62) | SLC9A1SMPD1TBXAS1KDRPTGS1 | |
| SCHEMBL20915262 | 0.67 | MEN1 (0.62) | SLC9A1SMPD1TBXAS1KDRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638681-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | Quretech Bio AB (SE) | 2020-04-22 | — | — | EP | claimed |
| WO-2018229141-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2018-12-20 | — | — | WO | claimed |
| EP-3638681-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | Quretech Bio AB (SE) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018229141-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2018-12-20 | — | — | WO | disclosed |